Evolution and ecology inspire clinical research in infections and antimicrobial resistance

Taking an evolutionary view can inspire new ideas in clinical microbiology. For example, evolutionary studies can reveal why some antimicrobial dosing regimens are better than others in preventing the development of drug resistance. Looking at microbial communities, rather than just pathogenic micro-organisms, can also lead to new insights. That is why clinicians, bioinformaticians analysing pathogens, and evolutionary biologists should all work together. These are the conclusions of a diverse group of scientists led by University of Groningen microbiologist Marjon de Vos, in a short review published by The Lancet Infectious Diseases on 30 April.